Product Description

IPYR Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES15438-50, ES15438-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The protein encoded by this gene is a member of the inorganic pyrophosphatase (PPase) family. PPases catalyze the hydrolysis of pyrophosphate to inorganic phosphate, which is important for the phosphate metabolism of cells. Studies of a similar protein in bovine suggested a cytoplasmic localization of this enzyme. [provided by RefSeq, Jul 2008],

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human IPYR AA range: 162-212

Isotype: IgG

Target: IPYR

Specificity: This antibody detects endogenous levels of IPYR at Human/Mouse

Dilution: WB 1：500-2000

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Expressed ubiquitously,

Molecular Weight (Da): 32kD

Fields: Oxidative phosphorylation

Function: Catalytic Activity: Diphosphate + H(2)O = 2 phosphate
Cofactor: Binds 4 magnesium ions per subunit. Other metal ions can support activity, but at a lower rate. Two magnesium ions are required for the activation of the enzyme and are present before substrate binds, two additional magnesium ions form complexes with substrate and product
Similarity: Belongs to the PPase family
Subunit: Homodimer
Tissue Specificity: Expressed ubiquitously

Subcellular Location: Cytoplasm

Storage and Stability: -20°C/1 year

Gene Name: PPA1 IOPPP PP

Protein Name: IPYR

Mouse Gene ID: 67895

Mouse SwissProt Number: Q9D819

Research Use Only