K6-linkage Specific Polyubiquitin Rabbit pAb - A18106

K6-linkage Specific Polyubiquitin Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A18106-20, A18106-100

Citations, Manuals and MSDS Available upon request.

Background: Polyubiquitin chains regulate diverse cellular processes through the ability of ubiquitin to form chains of eight different linkage types. Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair. it has been reported that modification at Lys-6 inhibits ubiquitin-dependent protein degradation, a failure of the ubiquitin-proteasome system could play a role in initiating the formation of degradation-resistant PHF tangles.

Category: Other Modified Antibodies

Applications: WB, DB, ELISA

Cross-reactivity: Mouse, Rat

Immunogen: Synthetic peptide

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:2000 DB, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

NCBI Alias: UBB

Research Use Only