K63-linkage Specific Polyubiquitin Rabbit pAb - A18164

K63-linkage Specific Polyubiquitin Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A18164-20, A18164-100

Citations, Manuals and MSDS Available upon request.

Background: Ubiquitination, onetypeofthemostcommonpost-translationalmodification, mediatestheregulationofproteinhomeostasisinvivo.SinceubiquitinitselfcontainsmultiplelysineresiduesandoneN-terminalfreeaminogroup, eighttypesofubiquitinchainscanbeformed.? K63-linked polyubiquitin chains exert nonproteolytic functions in vivo, such as protein trafficking, kinase/phosphatase activation, and DNA damage control, all of which might be important in regulation of cancer survival and development (PMID: 19217402，PMCID: PMC3008764).

Category: Other Modified Antibodies

Applications: DB, ELISA

Cross-reactivity: Human, Mouse, Rat, Other (Wide Range Predicted)

Observed Molecular Weight: 15-200kDa

Immunogen: Synthetic peptide

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.

Recommended Dilutions: DB, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

NCBI Alias: UBB

Research Use Only