[KD Validated] Bcl-2 Rabbit PolymAb® - A27315PM

[KD Validated] Bcl-2 Rabbit PolymAb®

Sizes: 20μL, 100μL

Catalogue Numbers: A27315PM-20, A27315PM-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.

Category: Monoclonal Antibodies

Applications: WB, IHC-P, ELISA

Cross-reactivity: Human, Mouse, Rat

Protein Weight: 26kDa

Observed Molecular Weight: 26kDa

Immunogen: Synthetic peptide .

Species: Human/Rat

GeneID: 596/24224

SWISS: P10415/P49950

Alternate Names: Bcl-2; PPP1R50

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide, 0.05% BSA, 50% glycerol, pH 7.3.

Recommended Dilutions: WB, 1:3000 - 1:18000 IHC-P, 1:200 - 1:800 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Protein phosphorylation, Cancer, Tumor biomarkers, Invasion and Metastasis, Signal Transduction, PI3K-Akt Signaling Pathway, Cell Biology Developmental Biology, Apoptosis, Mitochondrial Control of Apoptosis, Inhibition of Apoptosis, Autophagy, Death Receptor Signaling Pathway, Endocrine Metabolism, Mitochondrial metabolism, Mitochondrial markers, Immunology Inflammation, Neuroscience, Neurodegenerative Diseases, Stem Cells.

NCBI Alias: BCL2

Research Use Only