[KD Validated] COX7A2L Rabbit pAb - A23681

[KD Validated] COX7A2L Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A23681-20, A23681-100

Citations, Manuals and MSDS Available upon request.

Background: Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein similar to polypeptides 1 and 2 of subunit VIIa in the C-terminal region, and also highly similar to the mouse Sig81 protein sequence. This gene is expressed in all tissues, and upregulated in a breast cancer cell line after estrogen treatment. It is possible that this gene represents a regulatory subunit of COX and mediates the higher level of energy production in target cells by estrogen. Several transcript variants, some protein-coding and others non-protein coding, have been found for this gene.

Category: Polyclonal Antibodies

Applications: WB, ELISA

Cross-reactivity: Human

Protein Weight: 13kDa

Observed Molecular Weight: 14kDa

Immunogen: Recombinant protein (or fragment) .

Species: Human

GeneID: 9167

SWISS: O14548

Alternate Names: EB1; SCAF1; SCAFI; SIG81; COX7AR; COX7RP; [KD Validated] COX7A2L

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.

Recommended Dilutions: WB, 1:1000 - 1:5000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Cancer, Signal Transduction, Endocrine Metabolism, Mitochondrial metabolism, Mitochondrial markers, Neuroscience, Neurodegenerative Diseases.

NCBI Alias: COX7A2L

Research Use Only