[KD Validated] EGFR Rabbit PolymAb® - A24388PM

[KD Validated] EGFR Rabbit PolymAb®

Sizes: 20μL, 100μL

Catalogue Numbers: A24388PM-20, A24388PM-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.

Category: Monoclonal Antibodies

Applications: WB, IF/ICC, ELISA

Cross-reactivity: Human

Protein Weight: 44kDa/69kDa/77kDa/134kDa

Observed Molecular Weight: 145-175kDa

Immunogen: Recombinant protein (or fragment) .

Species: Human

GeneID: 1956

SWISS: P00533

Alternate Names: EGFR; ERBB; ERBB1; HER1; NISBD2; PIG61; mENA; epidermal growth factor receptor

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:2000 IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Cancer, Tumor biomarkers, Signal Transduction, G protein signaling, Kinase, Tyrosine kinases, Phospholipase Signaling Pathway, ErbB-HER Signaling Pathway, Cell Biology & Developmental Biology, Growth factor, EGF, Immunology & Inflammation, IL-6 Receptor Signaling Pat

NCBI Alias: EGFR

Research Use Only