Kdm6b Rabbit pAb - A12763

Kdm6b Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A12763-20, A12763-100

Citations, Manuals and MSDS Available upon request.

Background: Enables beta-catenin binding activity; histone H3-tri/di-methyl-lysine-27 demethylase activity; and sequence-specific DNA binding activity. Involved in several processes, including histone H3-K27 demethylation; mesodermal cell differentiation; and positive regulation of cold-induced thermogenesis. Acts upstream of or within several processes, including cellular response to hydrogen peroxide; histone demethylation; and positive regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including brain; gut; liver; metanephros; and olfactory epithelium. Orthologous to human KDM6B (lysine demethylase 6B).

Category: Polyclonal Antibodies

Applications: WB, IF/ICC, ELISA

Cross-reactivity: Human, Mouse

Protein Weight: 176kDa

Observed Molecular Weight: 170kDa

Immunogen: Recombinant protein (or fragment)

Species: Mouse

GeneID: 216850

Alternate Names: Jmjd3; 1700064E03Rik; Kdm6b

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide, 50% glycerol, pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:2000 IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Epigenetics & Nuclear Signaling, Chromatin Modifying Enzymes, Demethylation, Immunology & Inflammation.

NCBI Alias: Kdm6b

Research Use Only