Kif 7 Monoclonal Antibody (3F8) - BT-MCA0809

Kif 7 Monoclonal Antibody (3F8)

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-MCA0809-20, BT-MCA0809-50, BT-MCA0809-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies.

Research Areas: Signal transduction; Stem cells

Target Protein: KIF7

Applications: IHC-P, IF, ICC

Reactivity: Human,Mouse,Rat

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Kinesin-like protein KIF7

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q2M1P5; Mouse: B7ZNG0

Synonyms: Kinesin-like protein KIF7

GeneID: Human: 374654; Mouse: 16576

Research Use Only