[KO Validated] EDN1 Rabbit pAb - A18004

[KO Validated] EDN1 Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A18004-20, A18004-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family. This peptide is a potent vasoconstrictor and its cognate receptors are therapeutic targets in the treatment of pulmonary arterial hypertension. Aberrant expression of this gene may promote tumorigenesis. Alternative splicing results in multiple transcript variants.

Category: Polyclonal Antibodies

Applications: WB, IF/ICC, ELISA

Cross-reactivity: Human, Mouse, Rat

Protein Weight: 24kDa

Observed Molecular Weight: 24kDa

Immunogen: Recombinant protein (or fragment) .

Species: Human

GeneID: 1906

SWISS: P05305

Alternate Names: ET1; QME; PPET1; ARCND3; HDLCQ7; N1

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide, 50% glycerol, pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:2000 IF/ICC, 1:50 - 1:100 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Cancer, Signal Transduction, Cell Biology Developmental Biology, Growth factors, Endocrine Metabolism, Cardiovascular, Angiogenesis, Hypoxia.

NCBI Alias: EDN1

Research Use Only