[KO Validated] FH Rabbit pAb - A21403

[KO Validated] FH Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A21403-20, A21403-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy.

Category: Polyclonal Antibodies

Applications: WB, ELISA

Cross-reactivity: Human, Mouse, Rat

Protein Weight: 55kDa

Observed Molecular Weight: 49kDa

Immunogen: Synthetic peptide .

Species: Human

GeneID: 2271

SWISS: P07954

Alternate Names: MCL; FMRD; HsFH; LRCC; HLRCC; MCUL1; FH

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Cancer, Tumor suppressors, Signal Transduction, Endocrine Metabolism.

NCBI Alias: FH

Research Use Only