[KO Validated] Galectin 3/LGALS3 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A13506-20, A13506-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants.
Category: Polyclonal Antibodies
Applications: WB, IF/ICC, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 26kDa
Observed Molecular Weight: 28kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 3958
SWISS: P17931
Alternate Names: L31; GAL3; MAC2; CBP35; GALBP; GALIG; LGALS2; S3
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, RNA Binding, Cell Biology Developmental Biology, Cell Cycle, Cell differentiation, Cell Adhesion, Neuroscience.
NCBI Alias: LGALS3
Research Use Only