(KO Validated) HADHA Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-64551-60, E-AB-64551-120, E-AB-64551-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: HADHA
Target Synonym: HADHA; ECHA; GBP; HADH; LCEH; LCHAD; MTPA; TP-ALPHA
Research Areas: Cancer, Cardiovascular, Metabolism, Signal Transduction, Tags and Cell Markers
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse
Application: IHC, IF
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: P40939
Background: This gene encodes the alpha subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the alpha subunit catalyzing the 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase activities. Mutations in this gene result in trifunctional protein deficiency or LCHAD deficiency. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation.
Concentration: 1mg/mL
Immunogen: Recombinant fusion protein of human HADHA (NP_000173.2).
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Purification Method: Affinity purification
Dilution: IHC 1:50-1:200 IF 1:50-1:200
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only