[KO Validated] HADHA Rabbit PolymAb® - A24055PM

[KO Validated] HADHA Rabbit PolymAb®

Sizes: 20μL, 100μL

Catalogue Numbers: A24055PM-20, A24055PM-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes the alpha subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the alpha subunit catalyzing the 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase activities. Mutations in this gene result in trifunctional protein deficiency or LCHAD deficiency. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation.

Category: Monoclonal Antibodies

Applications: WB, IHC-P, IF/ICC, IP, ELISA

Cross-reactivity: Human, Mouse, Rat

Protein Weight: 83 kDa

Observed Molecular Weight: 80 kDa

Immunogen: Recombinant protein (or fragment) .

Species: Human

GeneID: 3030

SWISS: P40939

Alternate Names: GBP; ECHA; HADH; LCEH; MTPA; LCHAD; TP-ALPHA

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.

Recommended Dilutions: WB, 1:1000 - 1:4000 IHC-P, 1:200 - 1:800 IF/ICC, 1:200 - 1:800 IP, 0.5μg-4μg antibody for 200μg-400μg extracts of whole cells ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Cancer, Signal Transduction, Endocrine Metabolism, Mitochondrial metabolism, Mitochondrial markers, Lipid Metabolism, Cardiovascular, Lipids, Fatty Acids.

NCBI Alias: HADHA

Research Use Only