[KO Validated] HuR/ELAVL1 Rabbit pAb - A6089

[KO Validated] HuR/ELAVL1 Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A6089-20, A6089-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy.

Category: Polyclonal Antibodies

Applications: WB, IHC-P, IF/ICC, ELISA

Cross-reactivity: Human, Mouse

Protein Weight: 36kDa

Observed Molecular Weight: 36kDa

Immunogen: Synthetic peptide .

Species: Human

GeneID: 1994

SWISS: Q15717

Alternate Names: HUR; Hua; MelG; ELAV1; L1

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:1000 IHC-P, 1:50 - 1:200 IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Epigenetics Nuclear Signaling, RNA Binding, Endocrine Metabolism, AMPK Signaling Pathway.

NCBI Alias: ELAVL1

Research Use Only