[KO Validated] IFNAR2 Rabbit pAb - A21462

[KO Validated] IFNAR2 Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A21462-20, A21462-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The protein belongs to the type II cytokine receptor family. Mutations in this gene are associated with Immunodeficiency 45.

Category: Polyclonal Antibodies

Applications: WB, ELISA

Cross-reactivity: Human, Mouse, Rat

Protein Weight: 27kDa/37kDa/57kDa

Observed Molecular Weight: 95kDa

Immunogen: Recombinant protein (or fragment)

Species: Human

GeneID: 3455

Alternate Names: IFN-R; IMD45; IFNABR; IFNARB; IFN-R-2; IFN-alpha-REC; R2

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis),  pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Epigenetics Nuclear Signaling, Cancer, Tumor immunology, Signal Transduction, Immunology Inflammation, Cytokines, Cell Intrinsic Innate Immunity Signaling Pathway.

NCBI Alias: IFNAR2

Research Use Only