Product Description

(KO Validated) MSH2 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-92378-60, E-AB-92378-120, E-AB-92378-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: MSH2

Target Synonym: MSH2; COCA1; FCC1; HNPCC; HNPCC1; LCFS2; mutS homolog 2

Research Areas: Cancer, Epigenetics and Nuclear Signaling

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Rat

Application: WB, IP

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: P43246

Background: This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human MSH2

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IP 1:50-1:200

Calculated MW: 97kDa/104kDa

Observed MW: 105KDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only