[KO Validated] MYOF Rabbit pAb - A15427

[KO Validated] MYOF Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A15427-20, A15427-100

Citations, Manuals and MSDS Available upon request.

Background: Mutations in dysferlin, a protein associated with the plasma membrane, can cause muscle weakness that affects both proximal and distal muscles. The protein encoded by this gene is a type II membrane protein that is structurally similar to dysferlin. It is a member of the ferlin family and associates with both plasma and nuclear membranes. The protein contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. Two transcript variants encoding different isoforms have been found for this gene. Other possible variants have been detected, but their full-length nature has not been determined.

Category: Polyclonal Antibodies

Applications: WB, ELISA

Cross-reactivity: Human, Mouse

Protein Weight: 235kDa

Observed Molecular Weight: 250kDa

Immunogen: Recombinant protein (or fragment)

Species: Human

GeneID: 26509

SWISS: Q9NZM1

Alternate Names: HAE7; FER1L3; OF

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Cell Biology Developmental Biology, Cardiovascular.

NCBI Alias: MYOF

Research Use Only