[KO Validated] NDRG1 Rabbit pAb - A2142

[KO Validated] NDRG1 Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A2142-20, A2142-100

Citations, Manuals and MSDS Available upon request.

Background: This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. The encoded protein is necessary for p53-mediated caspase activation and apoptosis. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Category: Polyclonal Antibodies

Applications: WB, IF/ICC, ELISA

Cross-reactivity: Human, Mouse, Rat

Protein Weight: 43kDa

Observed Molecular Weight: 48kDa

Immunogen: Recombinant protein (or fragment) .

Species: Human

GeneID: 10397

SWISS: Q92597

Alternate Names: GC4; RTP; DRG1; NDR1; NMSL; TDD5; CAP43; CMT4D; DRG-1; HMSNL; RIT42; TARG1; PROXY1; G1

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide, 50% glycerol, pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:1000 IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Epigenetics Nuclear Signaling, Protein phosphorylation, Cancer, Invasion and Metastasis, Signal Transduction, Neuroscience, Neurodegenerative Diseases, Cardiovascular, Angiogenesis.

NCBI Alias: NDRG1

Research Use Only