Product Description

[KO Validated] NME1/NM23A Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A17999-20, A17999-100

Citations, Manuals and MSDS Available upon request.

Background: This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.

Category: Polyclonal Antibodies

Applications: WB, IF/ICC, ELISA

Cross-reactivity: Human, Mouse, Rat

Protein Weight: 17kDa

Observed Molecular Weight: 21kDa

Immunogen: Synthetic peptide .

Species: Human

GeneID: 4830

SWISS: P15531

Alternate Names: NB; AWD; NBS; GAAD; NDKA; NM23; NDPKA; NDPK-A; NM23-H1; 3A

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:2000 IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Epigenetics Nuclear Signaling, RNA Binding, Cancer, Tumor suppressors, Cell Biology Developmental Biology, Apoptosis, Neuroscience, Neurodegenerative Diseases Markers, Other Neurological disorders.

NCBI Alias: NME1

Research Use Only