[KO Validated] RBBP4 Rabbit pAb - A13934

[KO Validated] RBBP4 Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A13934-20, A13934-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. It is present in protein complexes involved in histone acetylation and chromatin assembly. It is part of the Mi-2 complex which has been implicated in chromatin remodeling and transcriptional repression associated with histone deacetylation. This encoded protein is also part of co-repressor complexes, which is an integral component of transcriptional silencing. It is found among several cellular proteins that bind directly to retinoblastoma protein to regulate cell proliferation. This protein also seems to be involved in transcriptional repression of E2F-responsive genes. Three transcript variants encoding different isoforms have been found for this gene.

Category: Polyclonal Antibodies

Applications: WB, ELISA, ChIP

Cross-reactivity: Human

Protein Weight: 48kDa

Observed Molecular Weight: 48kDa

Immunogen: Recombinant protein (or fragment)

Species: Human

GeneID: 5928

SWISS: Q09028

Alternate Names: NURF55; RBAP48; lin-53; P4

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. ChIP, 5μg antibody for 10μg-15μg of Chromatin

Research Areas: Epigenetics Nuclear Signaling, Chromatin Remodeling, Cancer, Tumor suppressors, Cell Biology Developmental Biology, Cell Cycle, Cell cycle inhibitors.

NCBI Alias: RBBP4

Research Use Only