[KO Validated] SAV1 Rabbit pAb - A18667

[KO Validated] SAV1 Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A18667-20, A18667-100

Citations, Manuals and MSDS Available upon request.

Background: WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in adult tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1) -associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor.

Category: Polyclonal Antibodies

Applications: WB, IHC-P, ELISA

Cross-reactivity: Human, Mouse, Rat

Protein Weight: 45kDa

Observed Molecular Weight: 45kDa

Immunogen: Recombinant protein (or fragment) .

Species: Human

GeneID: 60485

SWISS: Q9H4B6

Alternate Names: SAV; WW45; WWP4; V1

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis),  pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:2000 IHC-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Signal Transduction, Kinase, Cell Biology Developmental Biology.

NCBI Alias: SAV1

Research Use Only