[KO Validated] SETDB1 Rabbit pAb - A6145

[KO Validated] SETDB1 Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A6145-20, A6145-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described.

Category: Polyclonal Antibodies

Applications: WB, IF-P, ELISA

Cross-reactivity: Human, Mouse, Rat

Protein Weight: 143kDa

Observed Molecular Weight: 180kDa

Immunogen: Recombinant protein (or fragment) .

Species: Human

GeneID: 9869

SWISS: Q15047

Alternate Names: ESET; KG1T; KMT1E; TDRD21; H3-K9-HMTase4; B1

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:1000 IF-P, 1:100-1:300 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Epigenetics Nuclear Signaling, Epigenetic writers and erasers of core Histones.

NCBI Alias: SETDB1

Research Use Only