Product Description

KRIT1 Recombinant Rabbit mAb

Sizes: 50μl, 100μl

Catalogue Numbers: BS46933-50, BS46933-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes a protein containing four ankyrin repeats, a band 4.1/ezrin/radixin/moesin (FERM) domain, and mμltiple NPXY sequences. The encoded protein is localized in the nucleus and cytoplasm. It binds to integrin cytoplasmic domain-associated protein-1 alpha (ICAP1alpha), and plays a critical role in beta1-integrin-mediated cell proliferation. It associates with junction proteins and RAS-related protein 1A (Rap1A), which requires the encoded protein for maintaining the integrity of endothelial junctions. It is also a microtubμle-associated protein and may play a role in microtubμle targeting. Mutations in this gene resμlt in cerebral cavernous malformations. Mμltiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2009]

Category: Primary Antibody

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, IHC, ICC/IF

Alternate Names: CAM, CCM1

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant protein of human KRIT1

Dilution: WB: 1:1000 IHC: 1:20 ICC/IF: 1:20

Purification: Affinity Purification

Specificity: IgG

Molecular Weight: 84 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: O00522

Product: Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Research Use Only