Ku70 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A0883-20, A0883-100
Citations, Manuals and MSDS Available upon request.
Background: The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V (D) J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus.
Category: Polyclonal Antibodies
Applications: WB, IHC-P, IF/ICC, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 70kDa
Observed Molecular Weight: 70kDa
Immunogen: Synthetic peptide
Species: Human
GeneID: 2547
SWISS: P12956
Alternate Names: ML8; KU70; TLAA; CTC75; CTCBF; G22P1; Ku70
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:3000 - 1:18000 IHC-P, 1:50 - 1:200 IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, DNA Damage Repair, RNA Binding, Cancer, Cell Biology Developmental Biology, Cell Cycle.
NCBI Alias: XRCC6
Research Use Only