Product Description

KVβ.3 (Q327) Polyclonal Antibody

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Catalogue Numbers: BS9168-50, BS9168-100

Sizes: 50µl, 100µl

Swiss-Prot: O43448

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC

Background: The KV gene family encodes more than 30 proteins that comprise the subunits of the K+ channels, and they vary in their gating and permeation properties, subcellular distribution and expression patterns. Functional KV channels assemble as tetramers consisting of pore-forming α subunits (KV), which include the KV1, KV2, KV3 and KV4 proteins, and accessory or KV-subunits that modify the gating properties of the coexpressed KV subunits. KVβ.3 is an accessory K+ channel protein which regulates the activity of the poreforming α subunit and alters the functional properties of Kv1.5. KVβ.3 localizes to the cytoplasm and is expressed in the brain, with highest expression detected in the cerebellum, and weakest expression seen in the frontal and temporal lobes. No KVβ.3 expression is detected in the heart, spinal cord, lung, liver, kidney, pancreas, placenta or skeletal muscle.

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: KVβ.3 (Q327) polyclonal antibody detects endogenous levels of KVβ.3 protein.

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunohistochemistry (IHC) analyzes of KVβ.3 (Q327) pAb in paraffin-embedded human breast cancer tissue.

Bioworld Molecular Weight: ~44 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Alternative Name: Voltage-gated potassium channel subunit beta-3; k (+) channel subunit beta-3; Kv-beta-3; KCNAB3; KCNA3B; KV-β.3

Immunogen: Synthetic peptide, corresponding to amino acids 301-350 of Human KVβ.3.

Conjugate: Unconjugated

Modification: Unmodified