Product Description

LμlL1/TOR1AIP2 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS65796-50, BS65796-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: LμlL1 is a 470 amino acid endoplasmic reticμlum single-pass membrane protein belonging to the TOR1AIP family. LμlL1 interacts with torsinA, an essential AAA+ ATPase found in the endoplasmic reticμlum (ER) and nuclear envelope (NE) of higher eukaryotes. LμlL1 regμlates the distribution and activity of torsinA within the ER and NE lumen and reveals functional defects in mutant torsinA, which is responsible for DYT1 dystonia, a neurodevelopmental disease caused by an in-frame deletion (Deltagag) in the gene encoding torsinA. The gene encoding LμlL1 maps to human chromosome 1, which spans 260 million base pairs, contains over 3, 000 genes and comprises nearly 8% of the human genome.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep

Host: Rabbit

Applications: WB, IHC-P

Alternate Names: TOR1AIP2, IFRG15, Interferon responsive gene 15, LμlL1, Lumenal domain like LAP1, NET9, RP11-12M5.5, TOR1AIP2, Torsin 1A interacting protein 2, Torsin A interacting protein 2.

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: KLH conjugated synthetic peptide derived from human LμlL1:221-320/470

Dilution: WB=1:500-2000 IHC-P=1:100-500

Purification: affinity purified by Protein A

Specificity: LμlL1 Polyclonal Antibody detects endogenous levels of LμlL1 protein.

Molecular Weight: ~56kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -31°C long term. Avoid freeze-thaw cycles.

SwissProt: Q8NFQ8

Product: 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Research Use Only