LGR5 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A24460-20, A24460-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene.
Category: Polyclonal Antibodies
Applications: WB, FC, ELISA
Cross-reactivity: Human, Mouse
Observed Molecular Weight: 102kDa
Immunogen: Synthetic peptide
Species: Human
GeneID: 8549
SWISS: O75473
Alternate Names: FEX; HG38; GPR49; GPR67; GRP49; LGR5
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:1000 - 1:5000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cancer, Signal Transduction, G protein signaling, G-Protein-Coupled ReceptorsGPCR, Stem Cells.
NCBI Alias: LGR5
Research Use Only