LRRK2 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A0859-20, A0859-100
Citations, Manuals and MSDS Available upon request.
Background: This gene is a member of the leucine-rich repeat kinase family and encodes a protein with an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, a DFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40 domain. The protein is present largely in the cytoplasm but also associates with the mitochondrial outer membrane. Mutations in this gene have been associated with Parkinson disease-8.
Category: Polyclonal Antibodies
Applications: WB, IHC-P, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 286kDa
Observed Molecular Weight: 290kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 120892
SWISS: Q5S007
Alternate Names: PARK8; RIPK7; ROCO2; AURA17; DARDARIN; LRRK2
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 IHC-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction, Kinase, Cell Biology Developmental Biology, Autophagy, Neuroscience, Neurodegenerative Diseases, Dopamine Signaling in Parkinson's Disease, Neurodegenerative Diseases Markers.
NCBI Alias: LRRK2
Research Use Only