Product Description

MAPKAP Kinase 3 Recombinant Rabbit mAb

Sizes: 50μl, 100μl

Catalogue Numbers: BS46472-50, BS46472-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes a member of the Ser/Thr protein kinase family. This kinase functions as a mitogen-activated protein kinase (MAP kinase)- activated protein kinase. MAP kinases are also known as extracellμlar signal-regμlated kinases (ERKs), act as an integration point for mμltiple biochemical signals. This kinase was shown to be activated by growth inducers and stress stimμlation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses. This kinase was reported to interact with, phosphorylate and repress the activity of E47, which is a basic helix-loop-helix transcription factor known to be involved in the regμlation of tissue-specific gene expression and cell differentiation. Alternate splicing resμlts in mμltiple transcript variants that encode the same protein. [provided by RefSeq, Sep 2011]

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: WB, FC, IP

Alternate Names: 3PK, MK3, MK-3, MDPT3, MAPKAP3, MAPKAP-K3, MAPKAPK-3

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide of human MK-3

Dilution: WB: 1:2000-1:10000 FC: 1:20 IP: 1:20

Purification: Affinity Purification

Specificity: IgG

Molecular Weight: 43 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q16644

Product: Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Research Use Only