MCOLN2 Rabbit pAb - A18560

MCOLN2 Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A18560-20, A18560-100

Citations, Manuals and MSDS Available upon request.

Background: Mucolipins constitute a family of cation channel proteins with homology to the transient receptor potential superfamily. In mammals, the mucolipin family includes 3 members, MCOLN1 (MIM 605248), MCOLN2, and MCOLN3 (MIM 607400), that exhibit a common 6-membrane-spanning topology. Homologs of mammalian mucolipins exist in Drosophila and C. elegans. Mutations in the human MCOLN1 gene cause mucolipodosis IV (MIM 262650) (Karacsonyi et al., 2007 [PubMed 17662026]) .

Category: Polyclonal Antibodies

Applications: WB, ELISA

Cross-reactivity: Human, Rat

Protein Weight: 66kDa

Observed Molecular Weight: 75kDa

Immunogen: Recombinant protein (or fragment) .

Species: Human

GeneID: 255231

SWISS: Q8IZK6

Alternate Names: TRPML2; TRP-ML2; MCOLN2

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Cancer, Endocrine Metabolism.

NCBI Alias: MCOLN2

Research Use Only