Product Description

MGMT Recombinant Rabbit mAb

Sizes: 50μl, 100μl

Catalogue Numbers: BS46980-50, BS46980-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Alkylating agents are potent carcinogens that can resμlt in cell death, mutation and cancer. The protein encoded by this gene is a DNA repair protein that is involved in cellμlar defense against mutagenesis and toxicity from alkylating agents. The protein catalyzes transfer of methyl groups from O(6)-alkylguanine and other methylated moieties of the DNA to its own molecμle, which repairs the toxic lesions. Methylation of the genes promoter has been associated with several cancer types, including colorectal cancer, lung cancer, lymphoma and glioblastoma. [provided by RefSeq, Sep 2015]

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: WB, IHC

Alternate Names: 6-O-methylguanine-DNA methyltransferase, O-6-methylguanine-DNA-alkyltransferase

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide of human MGMT

Dilution: WB: 1:1000-1:5000 IHC: 1:50-1:200

Purification: Affinity Purification

Specificity: IgG

Molecular Weight: 22 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P16455

Product: Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Research Use Only