Mitofusin 2 Rabbit pAb - A13606

Mitofusin 2 Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A13606-20, A13606-100

Citations, Manuals and MSDS Available upon request.

Background: Predicted to enable several functions, including GTP binding activity; GTPase activity; and enzyme binding activity. Involved in mitochondrial fusion; parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization; and positive regulation of cold-induced thermogenesis. Acts upstream of or within blastocyst formation and camera-type eye morphogenesis. Located in microtubule cytoskeleton and mitochondrion. Is expressed in several structures, including brain; early conceptus; eye; heart; and oocyte. Used to study Charcot-Marie-Tooth disease type 2A2A. Human ortholog (s) of this gene implicated in Charcot-Marie-Tooth disease; Charcot-Marie-Tooth disease type 2A2A; Charcot-Marie-Tooth disease type 2A2B; and Charcot-Marie-Tooth disease type 6. Orthologous to human MFN2 (mitofusin 2).

Category: Polyclonal Antibodies

Applications: WB, IHC-P, ELISA

Cross-reactivity: Human, Mouse, Rat

Protein Weight: 68kDa/86kDa

Observed Molecular Weight: 80kDa

Immunogen: Recombinant protein (or fragment)

Species: Mouse

GeneID: 170731

Alternate Names: Fzo; D630023P19Rik; Mitofusin 2

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis),  pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:1000 IHC-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Cancer, Signal Transduction, Cell Biology & Developmental Biology, Apoptosis, Autophagy, Endocrine & Metabolism, Mitochondrial metabolism, Mitochondrial markers, Mitophagy fission and fusion, Neuroscience, Neurodegenerative Diseases, Mitochondrial Control of Autophagy.

NCBI Alias: Mfn2

Research Use Only