MMP9 Rabbit pAb
Sizes: 20µl, 100µl
Catalogue Numbers: A0289-20, A0289-100
Citations, Manuals and SDS Available upon request.
Background: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling.
Synonyms: GELB; CLG4B; MMP-9; MANDP2; MMP9
GeneID: 4318
Swiss Prot: P14780
Tested Applications: ELISA, WB, IHC-P, IF/ICC
Reactivity: Human, Mouse, Rat
Calculated Molecular Weight: 78kDa
Observed Molecular Weight: 96kDa
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 538-707 of human MMP9 (NP_004985.2).
Immunogen Species: Human
Host: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage Buffer: Store at -20℃. Avoid freeze / thaw cycles.|Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Recommended Dilutions: WB: 1:500 - 1:1000 | IHC-P: 1:50 - 1:200 | IF/ICC: 1:50 - 1:200
Research Areas: Cancer, Tumor biomarkers, Invasion and Metastasis, Signal Transduction, G protein signaling, G-Protein-Coupled Receptors Signaling to MAPK Erk, Cell Biology Developmental Biology, Apoptosis, Cytoskeleton, Extracellular Matrix, Ubiquitin, Cardiovascular, Angiogenesis
Modifications: Unmodified
Conjugate: Unconjugated
Positive Samples: K-562
Cellular Location: Secreted, Extra Cellular Matrix, Extra Cellular Space,
Keywords: 4318, sc-6840, sc-6841, sc-10737, 92 kDa gelatinase, 92 kDa type IV collagenase, CLG4B, Gelatinase B, GELB, Matrix metalloproteinase 9, MMP 9, MMP9, MANDP2, MMP-9, matrix metallopeptidase 9, matrix metalloproteinase-9, macrophage gelatinase, matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase), matrix metalloproteinase 9 (gelatinase B, type V collagenase, P14780, Matrix Metallopeptidase 9, Matrix Metalloproteinase 9 (Gelatinase B, 92kDa Gelatinase, 92kDa Type IV Collagenase), Matrix Metallopeptidase 9 (Gelatinase B, Matrix Metalloproteinase-9, 92 KDa Type IV Collagenase, Macrophage Gelatinase, Type V Collagenase, 92 KDa Gelatinase, EC 3.4.24.35, sc6840, sc 6840, sc6841, sc 6841, sc10737, sc 10737
Symbol: MMP9
Category: Polyclonal Antibodies
Research Use Only