Product Description

Monoamine Oxidase A (MAO-A) Inhibitor Screening Kit

Sizes: 48T, 96T

Catalogue Numbers: E-BC-D012-48, E-BC-D012-96

Lead times: 2-3 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Test Principle: Monoamine Oxidase (MAO) is a mitochondrial membrane binding enzyme, which is widely present in connective tissues and cell mitochondria of liver, kidney, small intestine, stomach, brain and other organs. MAO-A metabolizes neurotransmitters such as serotonin, dopamine, serotonin, epinephrine and norepinephrine. MOA inhibition increases levels of neurotransmitters and are used to treat depression, neurodegenerative diseases, and cardiovascular disease.
The detection principle of this kit: MAO-A can catalyze the substrate to produce fluorescent substances. After adding inhibitors, the generation of fluorescent substances will be inhibited, and the effect of inhibitors will be determined according to the degree of inhibition.

Abbreviation: MAO-A

Research Areas: Inhibitor Screening

Result Type: Enzyme activity

Detection Instrument: Fluorescence microplate reader

Detection Type: Fluorometric method

Tested Sample Types: Inhibitor

Assay Length: 1 h

Inter cv: 5.0-8.9%

Intra cv: 0.7-5.0%

Research Use Only