MRPL40 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A18191-20, A18191-100
Citations, Manuals and MSDS Available upon request.
Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Deletions in this gene may contribute to the etiology of velo-cardio-facial syndrome and DiGeorge syndrome.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human
Protein Weight: 24kDa
Observed Molecular Weight: 24kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 64976
SWISS: Q9NQ50
Alternate Names: URIM; L40mt; NLVCF; MRPL22; MRP-L22; MRP-L40; MRPL40
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Endocrine Metabolism, Mitochondrial metabolism.
NCBI Alias: MRPL40
Research Use Only