Product Description

MUC3A Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES11883-50, ES11883-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The mucin genes encode epithelial glycoproteins, some of which are secreted and some membrane bound. Each of the genes contains at least one large domain of tandemly repeated sequence that encodes the peptide sequence rich in serine and/or threonine residues, which carries most of the O-linked glycosylation (Gendler and Spicer, 1995 [PubMed 7778880]).[supplied by OMIM, Aug 2008],

Reactivity: Human, Rat, Mouse,

Host: Rabbit

Applications: IHC, IF

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from part region of human protein

Isotype: IgG

Target: MUC3A

Specificity: MUC3A Polyclonal Antibody detects endogenous levels of protein.

Dilution: IHC-p 1:50-300

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Expression: Broad specificity, small intestine, colon, colonic tumors, heart, liver, thymus, prostate, pancreas and gall bladder,

Observed Band (KD): 279kD

Function: Alternative Products: Additional isoforms seem to exist,Function: Major glycoprotein component of a variety of mucus gels. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces
Function: Major glycoprotein component of a variety of mucus gels. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. May be involved in ligand binding and intracellular signaling
PTM: Highly O-glycosylated and probably also N-glycosylated
Similarity: Contains 1 EGF-like domain
Similarity: Contains 1 SEA domain
Tissue Specificity: Broad specificity, small intestine, colon, colonic tumors, heart, liver, thymus, prostate, pancreas and gall bladder
Tissue Specificity: Fetal and adult small intestine and fetal and adult colon

Subcellular Location: [Isoform 1]: Membrane, Single-pass membrane protein, [Isoform 2]: Secreted, [Isoform 3]: Secreted, [Isoform 4]: Secreted, [Isoform 5]: Secreted

Storage and Stability: -20°C/1 year

Gene Name: MUC3A MUC3

Protein Name: Mucin-3A (MUC-3A) (Intestinal mucin-3A)

Research Use Only