Product Description

MYH6/7 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS60994-50, BS60994-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Myosin is a highly conserved, ubiquitously expressed protein that interacts with actin to generate the force for cellμlar movements. Conventional myosins are hexameric proteins consisting of two heavy chain subunits, a pair of nonphosphorylatable light chain subunits and a pair of phosphorylatable light chain subunits. Three general classes of myosin have been cloned: smooth muscle myosins, striated muscle myosins and non-muscle myosins. Contractile activity in smooth muscle is regμlated by the calcium/calmodμlin-dependent phosphorylation of myosin light chain (MLC) by myosin light chain kinase. Myosin heavy chains, which are encoded by the MYH gene family, contain Actin-activated ATPase activity which generates the motor function of myosin. Myosin heavy chains were initially isolated from a human fetal skeletal muscle and are the major determinant in the speed of contraction of skeletal muscle. Various isoforms of myosin heavy chains are differentially expressed depending on the functional activity of the muscle.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Myosin-6, Myosin heavy chain 6, Myosin heavy chain, cardiac muscle alpha isoform, MyHC-alpha, MYH6, MYHCA, Myosin-7, Myosin heavy chain 7, Myosin heavy chain slow isoform, MyHC-slow, Myosin heavy chain, cardiac muscle beta isoform, MyHC-beta, MYH7, MYHCB

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding Human MYH6.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: MYH6/7 polyclonal antibody detects endogenous levels of MYH6/7 protein.

Molecular Weight: ~ 260 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P13533/P12883

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only