Product Description

MYLIP Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS61709-50, BS61709-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regμlatory light chain (MRLC), LDLR, VLDLR and LRP8. Proteasomal degradation of MRLC leads to inhibit neurite outgrowth in presence of NGF by counteracting the stabilization of MRLC by saposin-like protein (CNPY2/MSAP) and reducing CNPY2-stimμlated neurite outgrowth. Acts as a sterol-dependent inhibitor of cellμlar cholesterol uptake by mediating ubiquitination and subsequent degradation of LDLR.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: E3 ubiquitin-protein ligase MYLIP, Inducible degrader of the LDL-receptor, Idol, Myosin regμlatory light chain interacting protein, MIR, RING-type E3 ubiquitin transferase MYLIP, MYLIP, BZF1, IDOL, BM-023, PP5242

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding to amino acids 150-200 of Human MYLIP.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: MYLIP polyclonal antibody detects endogenous levels of MYLIP protein.

Molecular Weight: ~ 49 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q8WY64

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only