MYOC Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A1589-20, A1589-100
Citations, Manuals and MSDS Available upon request.
Background: MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse
Protein Weight: 57kDa
Observed Molecular Weight: 65kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 4653
SWISS: Q99972
Alternate Names: GPOA; JOAG; TIGR; GLC1A; JOAG1; MYOC
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Neuroscience.
NCBI Alias: MYOC
Research Use Only