Na+ CP type VIIα rabbit pAb - ES7123

Na+ CP type VIIα rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES7123-50, ES7123-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes one of the many voltage-gated sodium channel proteins. For proper functioning of neurons and muscles during action potentials, voltage-gated sodium channels direct sodium ion diffusion for membrane depolarization. This sodium channel protein has some atypical characteristics; the similarity between the human and mouse proteins is lower compared to other orthologous sodium channel pairs. Also, the S4 segments, which sense voltage changes, have fewer positive charged residues that in other sodium channels; domain 4 has fewer arginine and lysine residues compared to other sodium channel proteins. Several alternatively spliced transcript variants exist, but the full-length natures of all of them remain unknown. [provided by RefSeq, Dec 2011],

Alternate Name: SCN7A; SCN6A; Sodium channel protein type 7 subunit alpha; Putative voltage-gated sodium channel subunit alpha Nax; Sodium channel protein cardiac and skeletal muscle subunit alpha; Sodium channel protein type VII subunit alpha

Source: Rabbit

Applications: WB; IHC

Dilution: WB 1:500-2000; IHC-p 1:50-300

Reactivity: Human; Monkey

Immunogen: The antiserum was produced against synthesized peptide derived from human SCN7A. AA range:771-820

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 200kD

Human Gene ID: 6332

Human SWISS Prot NO: Q01118

Subcellular Location: Cell membrane; Multi-pass membrane protein.

Research Use Only