NFkB p65 Monoclonal Antibody (5G6) - BT-MCA0064

NFkB p65 Monoclonal Antibody (5G6)

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-MCA0064-20, BT-MCA0064-50, BT-MCA0064-100

Citations, Manuals and MSDS Available upon request.

Background: NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.

Research Areas: Cardiovascular; Signal transduction; Metabolism; Cancer; Cell biology; Microbiology; Neuroscience; Epigenetics and nuclear signaling

Target Protein: RELA

Applications: WB, IHC-p, IF, ICC, IP

Reactivity: Human,Mouse,Rat

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Transcription factor p65

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 60219

UniProt Accession: Human: Q04206; Mouse: Q04207

Synonyms: RELA; NFKB3; Transcription factor p65; Nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3

GeneID: Human: 5970; Mouse: 19697

Research Use Only