Product Description

NKp46 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES2965-50, ES2965-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: function:Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.,PTM:N-glycosylated.,PTM:O-glycosylated.,similarity:Belongs to the natural cytotoxicity receptor (NCR) family.,similarity:Contains 2 Ig-like (immunoglobulin-like) domains.,subunit:Interacts with CD3Z and FCER1G.,tissue specificity:Selectively expressed by both resting and activated NK cells.,

Reactivity: Human, Rat, Mouse,

Host: Rabbit

Applications: WB, ELISA

Alternate Names: NCR1, LY94, Natural cytotoxicity triggering receptor 1, Lymphocyte antigen 94 homolog, NK cell-activating receptor, Natural killer cell p46-related protein, NK-p46, NKp46, hNKp46, CD antigen CD335

Clonality: Polyclonal

Immunogen: The antiserum was produced against synthesized peptide derived from human NCR1. AA range:145-194

Isotype: IgG

Target: NKp46

Specificity: NKp46 Polyclonal Antibody detects endogenous levels of NKp46 protein.

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Selectively expressed by both resting and activated NK cells,

Observed Band (KD): 40kD

Fields: Natural killer cell mediated cytotoxicity

Function: Function: Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis
PTM: N-glycosylated
PTM: O-glycosylated
Similarity: Belongs to the natural cytotoxicity receptor (NCR) family
Similarity: Contains 2 Ig-like (immunoglobulin-like) domains
Subunit: Interacts with CD3Z and FCER1G
Tissue Specificity: Selectively expressed by both resting and activated NK cells

Subcellular Location: Cell membrane, Single-pass type I membrane protein

Storage and Stability: -20°C/1 year

Gene Name: NCR1

Protein Name: Natural cytotoxicity triggering receptor 1

Mouse SwissProt Number: Q8C567

Research Use Only