nm23 Rabbit pAb - A24540

nm23 Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A24540-20, A24540-100

Citations, Manuals and MSDS Available upon request.

Background: This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by NME1) and 'B' (encoded by this gene) isoforms. Multiple alternatively spliced transcript variants have been found for this gene. Read-through transcription from the neighboring upstream gene (NME1) generates naturally-occurring transcripts (NME1-NME2) that encode a fusion protein comprised of sequence sharing identity with each individual gene product.

Category: Polyclonal Antibodies

Applications: IHC-P, ELISA

Cross-reactivity: Human, Rat

Protein Weight: 17kDa

Observed Molecular Weight: Refer to figures

Immunogen: Recombinant protein (or fragment)

Species: Human

GeneID: 4830/4831

SWISS: P15531/P22392

Alternate Names: NB; AWD; NBS; GAAD; NDKA; NM23; NDPKA; NDPK-A; NM23-H1; PUF; NDKB; NDPKB; NM23B; NDPK-B; NM23-H2; nm23

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.

Recommended Dilutions: IHC-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

NCBI Alias: NME1/NME2

Research Use Only