Product Description

NMBR Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES6395-50, ES6395-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes a 7-transmembrane G protein-coupled receptor that binds neuromedin B, which is a growth factor and mitogen for gastrointestinal epithelial tissue and for normal and neoplastic lung. This receptor may play a role in smooth muscle contraction, neuronal responses, and the regulation of cell growth. Antagonists of this receptor have a potential therapeutic use in inhibiting tumor cell growth. Polymorphisms in this gene may be associated with a susceptibility for schizophrenia. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2016],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IF, ELISA

Alternate Names: NMBR, Neuromedin-B receptor, NMB-R, Epididymis tissue protein Li 185a, Neuromedin-B-preferring bombesin receptor

Clonality: Polyclonal

Immunogen: The antiserum was produced against synthesized peptide derived from human NMBR. AA range:221-270

Isotype: IgG

Target: NMBR

Specificity: NMBR Polyclonal Antibody detects endogenous levels of NMBR protein.

Dilution: Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Expressed in epididymis (at protein level),

Observed Band (KD): 43kD

Fields: Neuroactive ligand-receptor interaction

Function: Function: Receptor for neuromedin-B
Similarity: Belongs to the G-protein coupled receptor 1 family

Subcellular Location: Cell membrane, Multi-pass membrane protein

Storage and Stability: -20°C/1 year

Gene Name: NMBR

Protein Name: Neuromedin-B receptor

Mouse Gene ID: 18101

Mouse SwissProt Number: O54799

Rat Gene ID: 25264

Rat SwissProt Number: P24053

Research Use Only