Product Description

NMUR1 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES4461-50, ES4461-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: caution:It is uncertain whether Met-1 or Met-24 is the initiator.,function:Receptor for the neuromedin-U and neuromedin-S neuropeptides.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in greatest abundance in peripheral organs, particularly in elements of the gastrointestinal and urogenital systems with highest levels in testes. In central nervous system structures express levels are much lower than those seen in peripheral organs. Within the CNS, has been detected in highest abundance in the cerebellum, dorsal root ganglia, hippocampus, and spinal cord.,

Reactivity: Human, Rat, Mouse,

Host: Rabbit

Applications: WB, IF, ELISA

Alternate Names: NMUR1, GPR66, Neuromedin-U receptor 1, NMU-R1, G-protein coupled receptor 66, G-protein coupled receptor FM-3

Clonality: Polyclonal

Immunogen: The antiserum was produced against synthesized peptide derived from human NMUR1. AA range:1-50

Isotype: IgG

Target: NMUR1

Specificity: NMUR1 Polyclonal Antibody detects endogenous levels of NMUR1 protein.

Dilution: Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Expressed in greatest abundance in peripheral organs, particularly in elements of the gastrointestinal and urogenital systems with highest levels in testes, In central nervous system structures express levels are much lower than those seen in peripheral organs, Within the CNS, has been detected in highest abundance in the cerebellum, dorsal root ganglia, hippocampus, and spinal cord,

Observed Band (KD): 48kD

Fields: Neuroactive ligand-receptor interaction

Function: Caution: It is uncertain whether Met-1 or Met-24 is the initiator
Function: Receptor for the neuromedin-U and neuromedin-S neuropeptides
Similarity: Belongs to the G-protein coupled receptor 1 family
Tissue Specificity: Expressed in greatest abundance in peripheral organs, particularly in elements of the gastrointestinal and urogenital systems with highest levels in testes. In central nervous system structures express levels are much lower than those seen in peripheral organs. Within the CNS, has been detected in highest abundance in the cerebellum, dorsal root ganglia, hippocampus, and spinal cord

Subcellular Location: Cell membrane, Multi-pass membrane protein

Storage and Stability: -20°C/1 year

Gene Name: NMUR1

Protein Name: Neuromedin-U receptor 1

Mouse SwissProt Number: O55040

Research Use Only