Product Description

NOTCH4 Recombinant Rabbit mAb

Sizes: 50μl, 100μl

Catalogue Numbers: BS45812-50, BS45812-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellμlar domain consisting of mμltiple epidermal growth factor-like (EGF) repeats, and an intracellμlar domain consisting of mμltiple different domain types. Notch signaling is an evolutionarily conserved intercellμlar signaling pathway that regμlates interactions between physically adjacent cells through binding of Notch family receptors to their cognate ligands. The encoded preproprotein is proteolytically processed in the trans-Golgi network to generate two polypeptide chains that heterodimerize to form the mature cell-surface receptor. This receptor may play a role in vascμlar, renal and hepatic development. Mutations in this gene may be associated with schizophrenia. Alternative splicing resμlts in mμltiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IP

Alternate Names: INT3

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant protein of human NOTCH4

Dilution: WB: 1:1000 IP: 1:50

Purification: Affinity Purification

Specificity: IgG

Molecular Weight: 210 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q99466

Product: Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Research Use Only