Product Description

NTT4 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES3827-50, ES3827-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The SLC6 family of proteins, which includes SLC6A17, acts as specific transporters for neurotransmitters, amino acids, and osmolytes like betaine, taurine, and creatine. SLC6 proteins are sodium cotransporters that derive the energy for solute transport from the electrochemical gradient for sodium ions (Hoglund et al., 2005 [PubMed 16125675]).[supplied by OMIM, Mar 2008],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, ELISA

Alternate Names: SLC6A17, NTT4, Sodium-dependent neutral amino acid transporter SLC6A17, Sodium-dependent neurotransmitter transporter NTT4, Solute carrier family 6 member 17

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from NTT4. at AA range: 240-320

Isotype: IgG

Target: NTT4

Specificity: NTT4 Polyclonal Antibody detects endogenous levels of NTT4 protein.

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Hippocampus,

Observed Band (KD): 81kD

Function: Function: Not yet known, orphan transporter
Similarity: Belongs to the sodium: neurotransmitter symporter (SNF) family

Subcellular Location: Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane, Multi-pass membrane protein Cell junction, synapse, postsynapse Cell junction, synapse, presynapse Localizes at synaptic junctions - at both pre- and post-synaptic sites - particularly in excitatory glutamatergic terminals

Storage and Stability: -20°C/1 year

Gene Name: SLC6A17

Protein Name: Sodium-dependent neutral amino acid transporter SLC6A17

Mouse Gene ID: 229706

Mouse SwissProt Number: Q8BJI1

Rat Gene ID: 613226

Rat SwissProt Number: P31662

Research Use Only