Product Description

NVL Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES3777-50, ES3777-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes a member of the AAA (ATPases associated with diverse cellular activities) superfamily. Multiple transcript variants encoding different isoforms have been found for this gene. Two encoded proteins, described as major and minor isoforms, have been localized to distinct regions of the nucleus. The largest encoded protein (major isoform) has been localized to the nucleolus and shown to participate in ribosome biosynthesis (PMID: 15469983, 16782053), while the minor isoform has been localized to the nucleoplasmin. [provided by RefSeq, Aug 2011],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, ELISA

Alternate Names: NVL, Nuclear valosin-containing protein-like, NVLp, Nuclear VCP-like protein

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from NVL. at AA range: 320-400

Isotype: IgG

Target: NVL

Specificity: NVL Polyclonal Antibody detects endogenous levels of NVL protein.

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Widely expressed, Highest level of expression in heart, placenta, skeletal muscle, pancreas and retina,

Observed Band (KD): 95kD

Fields: Ribosome biogenesis in eukaryotes

Function: PTM: Phosphorylated
Similarity: Belongs to the AAA ATPase family
Tissue Specificity: Widely expressed. Highest level of expression in heart, placenta, skeletal muscle, pancreas and retina

Subcellular Location: [Isoform 2]: Nucleus, nucleoplasm, [Isoform 1]: Nucleus, nucleolus Nucleus, nucleoplasm Expressed predominantly in the nucleolus Associates with pre-ribosomal particles in the nucleus

Storage and Stability: -20°C/1 year

Gene Name: NVL

Protein Name: Nuclear valosin-containing protein-like

Mouse Gene ID: 67459

Mouse SwissProt Number: Q9DBY8

Research Use Only