OREX Polyclonal Antibody - BT-AP12549

OREX Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP12549-20, BT-AP12549-50, BT-AP12549-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a hypothalamic neuropeptide precursor protein that gives rise to two mature neuropeptides, orexin A and orexin B, by proteolytic processing. Orexin A and orexin B, which bind to orphan G-protein coupled receptors HCRTR1 and HCRTR2, function in the regulation of sleep and arousal. This neuropeptide arrangement may also play a role in feeding behavior, metabolism, and homeostasis.

Research Areas: Metabolism; Neuroscience

Target Protein: HCRT

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Orexin

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: O43612; Mouse: O55241; Rat: O55232

Synonyms: Orexin;Hypocretin;Hcrt [Cleaved into: Orexin-A;Hypocretin-1;Hcrt1; Orexin-B;Hypocretin-2;Hcrt2]

GeneID: Human: 3060

Research Use Only