OXGR1 Polyclonal Antibody - BT-AP12574

OXGR1 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP12574-20, BT-AP12574-50, BT-AP12574-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a G protein-coupled receptor (GPCR) that belongs to the oxoglutarate receptor family within the GPCR superfamily. The encoded protein is activated by the citric acid intermediate, oxoglutarate, as well as several cysteinyl leukotrienes, including leukotrienes E4, C4 and D4, which are implicated in many inflammatory disorders. In mice, a knock-out of this gene leads to middle ear inflammation, changes in the mucosal epithelium, and an increase in fluid behind the eardrum, and is associated with hearing loss. Alternative splicing results in multiple transcript variants.

Research Areas: Signal transduction

Target Protein: OXGR1

Applications: WB, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: 2-oxoglutarate receptor 1

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q96P68; Mouse: Q6IYF8; Rat: Q6Y1R5

Synonyms: 2-oxoglutarate receptor 1;Alpha-ketoglutarate receptor 1;G-protein coupled receptor 80;G-protein coupled receptor 99;P2Y purinoceptor 15;P2Y15;P2Y-like GPCR;P2Y-like nucleotide receptor

GeneID: Human: 27199

Research Use Only